Metabolomics Society 3rd Annual Conference
Renold Building, The University of Manchester, Manchester, UK, 11 - 14 June 2007
Frontpage : Conference Programme
Conference Programme
The programme for the 3rd Metabolomics Scientific Meeting are listed below:
Day 1: Tuesday, 12 June 2007
| 09:00 - | Registration desk opens in Renold Building, Sackville Street. Posters to be hung. |
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| 12:00 - 13:00 | Finger lunch commence in Renold Building | ||
| 13:00 - 13:15 | Opening Comments from Roy Goodacre, Rima Rima Kaddurah-Daouk and Simon Gaskell | ||
| 13:15 - 14:15 | Plenary Speaker 1: Gary Siuzdak (Scripps Center for Mass Spectrometry, La Jolla, CA, USA) "Novel approaches for small molecule detection". |
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| 14:15 - 14:45 | Coffee Break | ||
| 14:45 - 16:45 |
Session 1: Metabolomics in health and disease Chairs: Rima Kaddurah-Daouk (Duke University, USA) & Ian Wilson (AstraZeneca, Alderely Park, UK) David Wishart (University of Alberta, Canada) "The human metabolome project: An update for 2007" Sabine Bahn (The Cambridge Centre for Neuropsychiatric Research) "Disease Biomarkers in first-onset Schizophrenia". Laura Schnackenberg (FDA, USA) "(36) Characterization of multi-age rodent pediatric models of toxicity". Carolyn Slupsky (University of Alberta, Canada) "(23) Can the etiology of pneumonia be determined using metabolomics?". Session 2: Fluxomics and pathway discovery; informatics meets isotopomer analysis Chairs: Jacky Snoep (University of Manchester, UK) & Masaru Tomita (Keio University, Japan) Uwe Sauer (ETH Zurich, Switzerland) "Molecular traffic through metabolic networks: data, principles and their prediction" Jörg Schwender (Brookhaven National Laboratory, USA) "Probing seed development by metabolic flux analysis" Masaru Tomita (to be confirmed) (Keio University, Japan) "(99) Large-scale multi-omics analyses for E. coli systems biology" Fionnuala Morrish (to be confirmed) (Fred Hutchinson Cancer Center, Seattle, USA) "(83) 13C NMR isotopomer analysis of metabolic network regulation by the oncogene c-MYC during cell cycle entry" |
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| 16:30 - 17:45 | Technology Showcases: Bruker "Bruker BioSpin and Bruker Daltonics"
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(Dr Manfred Spraul, Dr Gabriela Zurek) Don't miss the unique Bruker Technology Showcase on Day One of the Conference. Join both Bruker BioSpin and Bruker Daltonics on Tuesday 12th June at 16:30 and discover the world's only, fully integrated and dedicated solution for Metabolic Profiling. Our unique combination of NMR & LC-MS is the ideal platform for conducting metabolomics studies, traditional metabolism studies, and analyses of complex mixtures (more details click here). Join us for a beer and a snack in the Barnes Wallis Building. To register for this session please visit http://www.bruker.co.uk/showcase.htm [close] |
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| 18:00 - 19:00 | Welcome Drinks Reception |
Day 2: Wednesday, 13 June 2007
| 09:00 - | Exhibit Opens | ||
| 09:00 - 10:00 | Plenary speaker 2: Steve Oliver (University of Manchester, UK) "Metabolomics as a tool for functional genomics: studies in yeast". |
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| 10:00 - 10:30 | Coffee Break | ||
| 10:30 - 12:30 |
Session 3: Integrating metabolomics data with Systems Biology Models Chairs: Jan van der Greef (Leiden/TNO, Netherlands) & Douglas Kell (The University of Manchester, UK) Matthias Heinemann (ETH Zurich, Switzerland). "Insight from quantitative metabolome data via network-embedded thermodynamic analysis" Age Smilde (University of Amsterdam, The Netherlands) "Metabolomics as an essential module in systems biology models" Domenico Bellomo (University of Delft, The Netherlands) "(126) Reconstructing metabolic networks from perturbation experiments" Marc-Emmanuel Dumas (Ecole Normale SupĂ©rieure de Lyon, France) "(167) Metabolic profiling and statistical genomics of insulin resistance" Session 4: Environmental metabolomics Chairs: Mark Viant (`University of Birmingham, UK) & Dan Bearden (Center for Coastal Environmental Health and Biomolecular Research, USA) Tim Collette (Environmental Protection Agency, USA) "Metabolomics in small fish toxicology and ecological risk assessments" Jake Bundy (Imperial College London, UK) "Metabolomics and `non-model´ organisms – earthworms as a case study" Mark Viant (University of Birmingham, UK) "(213) Can metabolomics be used for environmental monitoring in free living aquatic wildlife? - Building the weight of evidence" Simone Rochfort (The Department of Primary Industries, Australia) "(30) Wine, soils and complex community interactions" |
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| 12:30 - 14:00 | Exhibition and Poster Session Finger Buffet Lunch |
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| 13:00 - 14:00 | Technology Showcases: Bio-Rad Laboratories, Inc. "Data Processing and Analysis – An Integrated Informatics Approach for Metabolomics Research"
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Authors: Michelle D' Souza, Regis Grenier, Gregory Banik Bio-Rad Laboratories, Inc., Informatics Division, Two Penn Center Plaza, Suite 800, 1500 John F. Kennedy Blvd, Philadelphia, PA 19102 Abstract: The ever-increasing demand for improved data analysis tools within the metabolomics research community initiated Bio-Rad Laboratories' development of an integrated analytical approach. This approach encompasses all the steps involved in such analyses from raw data processing to biomarker identification and integrates market-leading analytical, cheminformatics, and chemometrics tools from Bio-Rad and its partners into a single system. At the 3rd Metabolomics Society Meeting, a technical talk and a poster presentation introduced this new approach and integrated system. We invite you to join us for a brief discussion of Bio-Rad's overall analytical data management environment and the advances that have occurred since the last meeting. Areas of focus will include streamlined multivariate analysis, metabolite projection analysis (projecting a database of pure metabolite spectra onto a metabolomics analysis to highlight the metabolites that appear to change most in the study), and automated pathway identification (based upon the metabolites implicated in the metabolite projection analysis). Finally, we will share recent initiatives to provide easy and comprehensive access to spectral resources for educational institutions. [close the abstract] |
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| 14:00 - 16:00 |
Session 5: Drug Discovery Chairs: John Haselden (GlaxoSmithKline, UK) & Don Robertson (Pfizer, USA) Ina Schuppe-Koistinen (AstraZeneca, Sweden) "The application of metabolic profiling in preclinical and clinical drug development" Susan Connor (GlaxoSmithKline, UK) "Metabolomics in pharmaceutical R&D: Potential for biomarker discovery" Yutai Li (Merck, US) "(5) Metabolomic analysis of bile acids as biomarkers of hepatobiliary toxicity" Aalim Weljie (University of Calgary, Canada) "(139) Metabolite biomarkers of scleroderma elucidated using 1H NMR metabolomics" Session 6: Plant Metabolomics Chairs: Mike Beale (Rothamsted Research, UK) & George Harrigan (Monsanto, USA) Søren Bak (Danish Technical University, Lyngby, Denmark) "Lessons to be learned from metabolic engineering of cyanogenic glucosides" Rik de Vos (Plant Research International, Wageningen, The Netherlands) "QTL analysis of Arabidopsis RI lines by metabolomics" Joachim Kopka (to be confirmed) (Max Planck Institute of Molecular Plant Physiology, Germany) "(54) GC-EI-TOF-MS analysis of in-vivo carbon-partitioning into soluble metabolite pools of higher plants by monitoring isotope dilution after 13CO2 labelling" Kazuki Saito (RIKEN Plant Science Center/ Chiba University, Japan) "(169) High-throughput gene discovery through integration of metabolomics and transcriptomics in Arabidopsis thaliana" |
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| 16:00 - 18:00 | Exhibition and Poster Session Society Elections/Other |
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| 19:30 - | Conference Dinner/Party |
Day 3: Thursday, 14 June 2007
| 09:00 - 10:00 | Plenary speaker 3: Robert Hall (Centre for BioSystems Genomics, Wageningen, The Netherlands) "Metabolomics assisted plant breeding". |
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| 10:00 - 10:30 | Coffee Break | ||
| 10:30 - 12:30 |
Session 7: Nutrigenomics and metabolomics Chairs: Ben van Ommen (TNO Quality of Life, The Netherlands) & Bruce German (Nestle, Switzerland) Augustin Scalbert (INRA Centre de Rechereé de Clermont Ferrand/Theix, France) "Phytochemicals as prominent constituents of the human metabolome – from dietary exposure to health effects" Sunil Kochhar (Nestlé Research Center, Lausanne, Switzerland) "Nutri-metabonomics approach in understanding gut microbiome-mammalian metabolic interactions" Bruce Kristal (Brigham & Women's Hospital, Boston, USA) "(208) Validation of a metabolic profile for caloric intake in rats" Session 8: Novel technologies for metabolomics Chairs: Jules Griffin (University of Cambridge) & Teresa Fan (University of Louisville, USA) Rolf Gruetter (EPFL, Lausanne, Switzerland) "13C MRS-based metabolomics" Justin Wiseman (Prosolia, Inc. Indianapolis, USA) "Desorption electrospray ionization (DESI) MS: a new tool for metabolomics" Matej Oresic (VTT Technical Research Centre of Finland, Finland) "(18) Comprehensive metabolomic characterisation of lipoprotein fractions reveals differential lipoprotein-specific regulation of xenobiotic and pro-inflammatory metabolites in patients with metabolic syndrome" Seetharaman Vaidyanathan (The University of Manchester, UK) "(59) Biomolecular imaging using ToF-SIMS and buckminsterfullerene (C60) primary ions to study spatial metabolite distribution in cells" |
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| 12:30 - 14:00 | Exhibition and Poster Session Finger Buffet Lunch |
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| 13:00 - 14:00 | Technology Showcases | ||
| 14:00 - 16:00 |
Session 9: Microbial Metabolomics Chair: Jørn Smedsgaard (Technical University of Denmark) & Pedro Mendes (Virginia Bioinformatics Institute, USA) Vladimir Shulaev (Virginia Bioinformatics Institute, USA) "Metabolic responses of Plasmodium falciparum to anti-malarial drugs" Gianni Panagiotou (Technical University of Denmark) "Metabolomics for genotyping aspergilli" Mariët J. van der Werf (TNO, The Netherlands) "(12) Strain improvement using metabolomics information" Judy Hwang (UC Berkeley, USA) "(138) Mapping metabolic pathways in the metal reducer, Shewanella oneidensis MR-1" Session 10: Bioinformatic strategies for metabolomics Chairs: Susanna-Assunta Sansone (EBI, UK) & Thomas Moritz (University of Umeå, Sweden) Nigel Hardy (University of Wales, Aberystwyth, UK) "Turning Metabolomics Reporting Requirements into useful software and biological output" Johan Trygg (University of Umeå, Sweden) "The OPLS and O2PLS approach in metabolomics and metabonomics" Margriet Hendriks (Univ Medical Centre, Utrecht, The Netherlands) "(32) Simplivariate methods: creating interpretable metabolomics models" Lily Tong (MIT, USA) "(93) Investigation of processing and imputation in metabolomics datasets" |
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| 16:00 - 16:30 | Coffee Break | ||
| 16:30 - 17:30 | Plenary speaker 4: Bernhard Palsson (University of California at San Diego, La Jolla, CA, USA) "Systems biology and metabolomics: mapping the human metabolome" | ||
| 17:30 - 17:45 | Closing Remarks |
Sessions Chairs
| 1. Metabolomics in Health and Disease: | |
| Rima Kaddurah-Daouk | (Duke University Medical Center, USA) |
| Ian Wilson | (AstraZeneca, Alderely Park, UK) |
| 2. Fluxomics and Pathway Discovery; Informatics Meets Isotopomer Analysis: | |
| Jacky Snoep | (University of Manchester, UK) |
| Masaru Tomita | (Keio University, Japan) |
| 3. Integrating Metabolomics Data with Systems Biology Models: | |
| Pedro Mendes | (Virginia Bioinformatics Institute, USA) |
| Jan van der Greef | (Leiden/TNO, Netherlands) |
| 4. Environmental Metabolomics: | |
| Mark Viant | (University of Birmingham, UK) |
| Dan Bearden | (Center for Coastal Environmental Health and Biomolecular Research, USA) |
| 5. Drug Discovery: | |
| John Haselden | (GlaxoSmithKline, UK) |
| Don Robertson | (Pfizer, USA) |
| 6. Plant Metabolomics: | |
| Mike Beale | (Rothamsted Research, UK) |
| George Harrigan | (Monsanto, USA) |
| 7. Nutrigenomics and Metabolomics: | |
| Ben van Ommen | (TNO Quality of Life, Netherlands) |
| Bruce German | (Nestle, Switzerland) |
| 8. Novel Technologies for Metabolomics: | |
| Jules Griffin | (University of Cambridge) |
| Teresa Fan | (University of Louisville, USA) |
| 9. Microbial Metabolomics: | |
| Jørn Smedsgaard | (Technical University of Denmark, Denmark) |
| 10. Bioinformatic Strategies for Metabolomics: | |
| Susanna-Assunta Sansone | (EBI, UK) |
| Thomas Moritz | (University of Umeå, Sweden) |